Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep907 | Reproductive and Developmental Endocrinology | ECE2023

Synergy between vitamin D and estradiol in PCOS patients affected by COVID-19 infection

Velija Asimi Zelija , Hajrovic Dzevad , Behmen Selma , Burekovic Azra

Introduction: Polycystic ovary syndrome (PCOS) affects 5-10% of reproductive aged women. PCOS also manifests a chronic pro-inflammatory state. Estradiol is known to modulate the actions of immune cells, and, therefore, the antiviral mechanisms of these cells could also be modified by this hormone stimulus. In the presence of vitamin D, the binding energy of the spike protein to ACE2 was increased and transferring Apo to Locked S conformer of spike trimer was facilitated. Toget...